Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50047928
Affinity DataKi: 0.5nMAssay Description:Inhibition of human factor 11a using pyroGlu-Pro-Arg-pNA.HCl substrateMore data for this Ligand-Target Pair
Affinity DataKd: <1nMAssay Description:Binding affinity to of human partial length VGFR2 expressed in mammalian system by active site-directed competition binding assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataKd: <1nMAssay Description:Binding affinity to of human partial length RET expressed in bacterial system by active site-directed competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant MMP13 using thiopeptide as chromogenic substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.30E+3nMAssay Description:Binding affinity to of humanised RAD51 C-terminal ATPase domain (with deletion of L2 loop residues 288 to 314) from Pyrococcus furiosus expressed in ...More data for this Ligand-Target Pair
Affinity DataKi: 7.00E+4nMAssay Description:Inhibition of human factor 11a using pyroGlu-Pro-Arg-pNA.HCl substrateMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 5.70E+5nMAssay Description:Binding affinity to of humanised RAD51 C-terminal ATPase domain (with deletion of L2 loop residues 288 to 314) from Pyrococcus furiosus expressed in ...More data for this Ligand-Target Pair
