Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50000721
TargetAmine oxidase [flavin-containing] B(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM23415(5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataKi:  49nMAssay Description:Inhibition of recombinant human MAO-B after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM23415(5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM23415(5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataKi:  59nMAssay Description:Competitive inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using varying levels of kynuramine as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM23415(5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50: 121nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50105417(CHEMBL1089 | Nardil | Phenethyl-hydrazine | PHENEL...)
Affinity DataKi:  124nMAssay Description:Mixed-type inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using varying levels of kynuramine as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50049391(norizalpinin | 3,5,7-trihydroxy-2-phenyl-4H-benzop...)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50105417(CHEMBL1089 | Nardil | Phenethyl-hydrazine | PHENEL...)
Affinity DataIC50: 143nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50105417(CHEMBL1089 | Nardil | Phenethyl-hydrazine | PHENEL...)
Affinity DataKi:  163nMAssay Description:Mixed-type inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using varying levels of kynuramine as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50105417(CHEMBL1089 | Nardil | Phenethyl-hydrazine | PHENEL...)
Affinity DataIC50: 238nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataIC50: 640nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50049391(norizalpinin | 3,5,7-trihydroxy-2-phenyl-4H-benzop...)
Affinity DataIC50: 3.65E+3nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 3.87E+4nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM23419(CHEMBL9352 | (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl...)
Affinity DataIC50: 2.88E+5nMAssay Description:Inhibition of recombinant human MAO-B after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM23419(CHEMBL9352 | (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl...)
Affinity DataIC50: 9.55E+5nMAssay Description:Mixed-type inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using varying levels of kynuramine as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed