Compile Data Set for Download or QSAR
maximum 50k data
Found 39 Enz. Inhib. hit(s) with all data for entry = 50049012
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230355(CHEMBL4061884)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of PHGDH (unknown origin) by FLINT methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM195606(NCT-503)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM195605(NCT-502 | US11225469, Compound 72)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232861(CHEMBL2131647 | US11225469, Compound 24)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230362(CHEMBL4070806)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of PHGDH (unknown origin) expressed in Escherichia coli BL21 using 3-phosphoglycerate as substrate preincubated for 4 hrs followed by subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM58473(MLS001172437 | N-(4-methyl-2-pyridinyl)-4-[3-(trif...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230362(CHEMBL4070806)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of PHGDH (unknown origin) expressed in Escherichia coli BL21 using 3 -phosphoglycerate as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232864(CHEMBL4060200)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232881(CHEMBL4089953)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232857(CHEMBL4067810)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232863(CHEMBL4082083)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232868(CHEMBL4087786)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232870(CHEMBL4071292)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232878(CHEMBL4095492)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232862(CHEMBL4103667)
Affinity DataIC50: <5.00E+4nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM195607(PHGDH-inactive | US11225469, Compound 71)
Affinity DataIC50: >5.70E+4nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232860(CHEMBL3125071 | US11225469, Compound 23)
Affinity DataIC50: >5.70E+4nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232872(CHEMBL4102836)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232871(CHEMBL4092091)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232869(CHEMBL4075057)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232867(CHEMBL1438334)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232866(CHEMBL4093068)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232865(CHEMBL4103244)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232859(CHEMBL4085313)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232858(CHEMBL4095229)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232856(CHEMBL4087527)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232855(CHEMBL4105394)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232854(CHEMBL4079651)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232852(CHEMBL4068860)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232853(CHEMBL4097684)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232877(CHEMBL579882 | TCMDC-124310)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length PHGDH (unknown origin) using 3-phosphoglycerate as substrate incubated for 60 mins in presence of PSAT1, PSPH by resazurin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232875(CHEMBL1901807)
Affinity DataKd:  5.90E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232874(CHEMBL4074617)
Affinity DataKd:  1.60E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232873(CHEMBL4084029)
Affinity DataKd:  5.80E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232880(Benzo[D]Isoxazol-3-Ol | CHEMBL444173)
Affinity DataKd:  6.50E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50230355(CHEMBL4061884)
Affinity DataKd:  180nMAssay Description:Binding affinity to PHGDH (unknown origin) by surface plasma resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232879(CHEMBL326430)
Affinity DataKd:  1.50E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232876(CHEMBL4094048)
Affinity DataKd:  2.80E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50011537(CHEMBL3262562)
Affinity DataKd:  9.30E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair