Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 50048932
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229873BDBM50229873(CHEMBL4088217)
Affinity DataKi:  0.840nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229867BDBM50229867(CHEMBL4098389)
Affinity DataKi:  0.890nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229738BDBM50229738(CHEMBL4087027)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229872BDBM50229872(CHEMBL4059973)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229758BDBM50229758(CHEMBL4102962)
Affinity DataKi:  3nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229997BDBM50229997(CHEMBL4065450)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229866BDBM50229866(CHEMBL4069650)
Affinity DataKi:  4.5nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229743BDBM50229743(CHEMBL4071691)
Affinity DataKi:  6nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229735BDBM50229735(CHEMBL4102477)
Affinity DataKi:  6.5nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229744BDBM50229744(CHEMBL4104497)
Affinity DataKi:  6.80nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229736BDBM50229736(CHEMBL4074219)
Affinity DataKi:  8.80nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229734BDBM50229734(CHEMBL4064568)
Affinity DataKi:  9nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229987BDBM50229987(CHEMBL4095948)
Affinity DataKi:  9.30nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229996BDBM50229996(CHEMBL4066341)
Affinity DataKi:  10nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229992BDBM50229992(CHEMBL4080261)
Affinity DataKi:  10nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229874BDBM50229874(CHEMBL4074453)
Affinity DataKi:  12nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229980BDBM50229980(CHEMBL4101024)
Affinity DataKi:  13nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230023BDBM50230023(CHEMBL4094726)
Affinity DataKi:  14nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229737BDBM50229737(CHEMBL4065597)
Affinity DataKi:  15nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230018BDBM50230018(CHEMBL4084044)
Affinity DataKi:  18nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229976BDBM50229976(CHEMBL4098557)
Affinity DataKi:  20nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229849BDBM50229849(CHEMBL4090666)
Affinity DataKi:  27nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229994BDBM50229994(CHEMBL4095870)
Affinity DataKi:  28nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230020BDBM50230020(CHEMBL4062902)
Affinity DataKi:  29nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229753BDBM50229753(CHEMBL4076870)
Affinity DataKi:  29nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229754BDBM50229754(CHEMBL4075523)
Affinity DataKi:  31nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229875BDBM50229875(CHEMBL4077847)
Affinity DataKi:  32nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229989BDBM50229989(CHEMBL4084518)
Affinity DataKi:  34nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229876BDBM50229876(CHEMBL4085699)
Affinity DataKi:  37nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229755BDBM50229755(CHEMBL4061253)
Affinity DataKi:  38nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229757BDBM50229757(CHEMBL4081537)
Affinity DataKi:  39nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229756BDBM50229756(CHEMBL4089409)
Affinity DataKi:  40nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229979BDBM50229979(CHEMBL4090836)
Affinity DataKi:  47nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229746BDBM50229746(CHEMBL4070709)
Affinity DataKi:  51nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230019BDBM50230019(CHEMBL4085018)
Affinity DataKi:  57nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229733BDBM50229733(CHEMBL4092261)
Affinity DataKi:  59nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229747BDBM50229747(CHEMBL4083175)
Affinity DataKi:  71nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229752BDBM50229752(CHEMBL4060539)
Affinity DataKi:  72nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229986BDBM50229986(CHEMBL4065820)
Affinity DataKi:  78nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229990BDBM50229990(CHEMBL4101795)
Affinity DataKi:  83nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230024BDBM50230024(CHEMBL4080363)
Affinity DataKi:  92nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229745BDBM50229745(CHEMBL4099601)
Affinity DataKi:  94nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229732BDBM50229732(CHEMBL4083791)
Affinity DataKi:  99nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229981BDBM50229981(CHEMBL4083046)
Affinity DataKi:  104nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229884BDBM50229884(CHEMBL4089914)
Affinity DataKi:  111nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230022BDBM50230022(CHEMBL4077206)
Affinity DataKi:  114nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229995BDBM50229995(CHEMBL4069735)
Affinity DataKi:  120nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229877BDBM50229877(CHEMBL4103630)
Affinity DataKi:  132nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230021BDBM50230021(CHEMBL4093432)
Affinity DataKi:  143nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229748BDBM50229748(CHEMBL4069986)
Affinity DataKi:  156nMAssay Description:Inhibition of human beta factor 12a using fluorogenic substrate Boc-Gln-Gly-Arg-AMC preincubated for 10 mins followed by addition of substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2019
Entry Details Article
PubMed
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