Found 53 Enz. Inhib. hit(s) with all data for entry = 50048940 
Affinity DataKi: 0.0300nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 0.470nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.880nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of human plasma kallikrein using H-(D)-Pro-Phe-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of human plasma kallikrein using H-(D)-Pro-Phe-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 159nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 184nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 25 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 264nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 420nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 25 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 514nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 519nMAssay Description:Inhibition of human plasma kallikrein using H-(D)-Pro-Phe-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 636nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.67E+3nMAssay Description:Inhibition of human coagulation factor 7a using H-(D)-Ile-Pro-Arg-pNA as substrate after 10 to 120 mins at 25 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >3.05E+3nMAssay Description:Inhibition of human coagulation factor 12a using H-(D)-CHT-Gly-Arg-pNA as substrate after 10 to 120 mins at 25 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >3.05E+3nMAssay Description:Inhibition of human coagulation factor 12a using H-(D)-CHT-Gly-Arg-pNA as substrate after 10 to 120 mins at 25 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >3.05E+3nMAssay Description:Inhibition of human coagulation factor 12a using H-(D)-CHT-Gly-Arg-pNA as substrate after 10 to 120 mins at 25 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.19E+3nMAssay Description:Inhibition of human coagulation factor 7a using H-(D)-Ile-Pro-Arg-pNA as substrate after 10 to 120 mins at 25 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.92E+3nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 5.05E+3nMAssay Description:Inhibition of human urokinase using pyro-Glu-Gly-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >6.15E+3nMAssay Description:Inhibition of human tissue plasminogen activator using methylsulfonyl-D-cyclohexylalanyl-GlyArg-pNA as substrate after 10 to 120 mins at 37 degC by s...More data for this Ligand-Target Pair
Affinity DataKi: >6.15E+3nMAssay Description:Inhibition of human tissue plasminogen activator using methylsulfonyl-D-cyclohexylalanyl-GlyArg-pNA as substrate after 10 to 120 mins at 37 degC by s...More data for this Ligand-Target Pair
Affinity DataKi: >6.15E+3nMAssay Description:Inhibition of human tissue plasminogen activator using methylsulfonyl-D-cyclohexylalanyl-GlyArg-pNA as substrate after 10 to 120 mins at 37 degC by s...More data for this Ligand-Target Pair
Affinity DataKi: >1.15E+4nMAssay Description:Inhibition of human thrombin using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.15E+4nMAssay Description:Inhibition of human thrombin using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.15E+4nMAssay Description:Inhibition of human thrombin using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of human coagulation factor 10a using N-benzoyl-Ile-Glu-(OH,OMe)-Gly-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotom...More data for this Ligand-Target Pair
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of human coagulation factor 10a using N-benzoyl-Ile-Glu-(OH,OMe)-Gly-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotom...More data for this Ligand-Target Pair
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of human coagulation factor 10a using N-benzoyl-Ile-Glu-(OH,OMe)-Gly-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotom...More data for this Ligand-Target Pair
Affinity DataKi: >1.34E+4nMAssay Description:Inhibition of human coagulation factor 7a using H-(D)-Ile-Pro-Arg-pNA as substrate after 10 to 120 mins at 25 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.42E+4nMAssay Description:Inhibition of human plasmin using H-(D)-Val-Leu-LyspNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: >1.51E+4nMAssay Description:Inhibition of human urokinase using pyro-Glu-Gly-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: >1.51E+4nMAssay Description:Inhibition of human urokinase using pyro-Glu-Gly-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.52E+4nMAssay Description:Inhibition of human plasmin using H-(D)-Val-Leu-LyspNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.52E+4nMAssay Description:Inhibition of human plasmin using H-(D)-Val-Leu-LyspNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >2.15E+4nMAssay Description:Inhibition of human activated protein C using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >2.15E+4nMAssay Description:Inhibition of human activated protein C using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: >2.15E+4nMAssay Description:Inhibition of human activated protein C using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
