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Found 5 Enz. Inhib. hit(s) with all data for entry = 50048983
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50232421(CHEMBL4100501)
Affinity DataIC50:  100nMAssay Description:Inhibition of human c-RAF using MEK1 as substrate in presence of [33P]ATP by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50232423(CHEMBL4065090)
Affinity DataIC50:  150nMAssay Description:Inhibition of human c-RAF using MEK1 as substrate in presence of [33P]ATP by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50232422(CHEMBL4073684)
Affinity DataIC50:  220nMAssay Description:Inhibition of human c-RAF using MEK1 as substrate in presence of [33P]ATP by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50232424(CHEMBL4097123)
Affinity DataIC50:  370nMAssay Description:Inhibition of human c-RAF using MEK1 as substrate in presence of [33P]ATP by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50232421(CHEMBL4100501)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of human BRAF using MEK1 as substrate in presence of [33P]ATP by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed