Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50006630
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501345BDBM50501345(CHEMBL3958857)
Affinity DataKi:  9nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501343BDBM50501343(CHEMBL3922435)
Affinity DataKi:  280nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501342BDBM50501342(CHEMBL3904433)
Affinity DataKi:  374nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501347BDBM50501347(CHEMBL3935647)
Affinity DataKi:  380nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501344BDBM50501344(CHEMBL3932440)
Affinity DataKi:  382nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501341BDBM50501341(CHEMBL3897666)
Affinity DataKi:  920nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501332BDBM50501332(CHEMBL3982443)
Affinity DataKi:  1.60E+3nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501335BDBM50501335(CHEMBL3940601)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501339BDBM50501339(CHEMBL3961855)
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501350BDBM50501350(CHEMBL3974440)
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501334BDBM50501334(CHEMBL3953729)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501333BDBM50501333(CHEMBL3968831)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501337BDBM50501337(CHEMBL3941415)
Affinity DataKi:  8.00E+3nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501338BDBM50501338(CHEMBL3911460)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501348BDBM50501348(CHEMBL3913450)
Affinity DataKi:  1.52E+4nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501340BDBM50501340(CHEMBL3936077)
Affinity DataKi: >2.00E+4nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501349BDBM50501349(CHEMBL3981450)
Affinity DataKi: >2.50E+4nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501336BDBM50501336(CHEMBL3965944)
Affinity DataKi:  3.60E+4nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501346BDBM50501346(CHEMBL3945018)
Affinity DataKi:  5.00E+4nMAssay Description:Binding affinity to GMP-stabilized FLAG-tagged KRAS G12C mutant (unknown origin) using desthiobiotin-GTP probe by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed