Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50048946
LigandPNGBDBM50230926(CHEMBL4083504)
Affinity DataIC50: 0.870nMAssay Description:Inhibition of PI3K p110delta (unknown origin) using PIP2 as substrate after 1 hr by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230930(CHEMBL4061892)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230652(CHEMBL4101502)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230926(CHEMBL4083504)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230924(CHEMBL4060665)
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230921(CHEMBL4065830)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230651(CHEMBL4093445)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230654(CHEMBL4093568)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230723(CHEMBL4104976)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230926(CHEMBL4083504)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant full length human N-terminal His6-tagged PI3K p110beta/p85alpha expressed in baculovirus infected Sf21 cells using PIP2 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230925(CHEMBL4080749)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230928(CHEMBL4080073)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230926(CHEMBL4083504)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant full length His-tagged human PI3K p110gamma expressed in baculovirus expression system using PIP2 as substrate after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230922(CHEMBL4101664)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50230926(CHEMBL4083504)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362-end residues) using ULight-4E-BP1 peptide substrate after 1 hr in presence of ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230722(CHEMBL4072061)
Affinity DataIC50: 15nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant full length human N-terminal His6-tagged PI3K p110beta/p85alpha expressed in baculovirus infected Sf21 cells using PIP2 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362-end residues) using ULight-4E-BP1 peptide substrate after 1 hr in presence of ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant full length His-tagged human PI3K p110gamma expressed in baculovirus expression system using PIP2 as substrate after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230653(CHEMBL4069347)
Affinity DataIC50: 27nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230923(CHEMBL4102264)
Affinity DataIC50: 30nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 35nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230929(CHEMBL4090377)
Affinity DataIC50: 36nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 89nMAssay Description:Inhibition of PI3K p110delta (unknown origin) using PIP2 as substrate after 1 hr by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50230927(CHEMBL4074980)
Affinity DataIC50: 210nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed