Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50006654
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50187693(CHEMBL3186509)
Affinity DataIC50: 3nMAssay Description:Inhibition of human ATX expressed in HEK293 cells using FS-3 as substrate after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501623(CHEMBL4062929)
Affinity DataKi:  6nMAssay Description:Competitive inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in LPC hydrolysis measured every 30 secs for 90 mins by Lin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501623(CHEMBL4062929)
Affinity DataIC50: 20nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501636(CHEMBL4093316)
Affinity DataIC50: 100nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501631(CHEMBL4081367)
Affinity DataIC50: 129nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501630(CHEMBL4105619)
Affinity DataIC50: 202nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501624(CHEMBL4090866)
Affinity DataIC50: 208nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501633(CHEMBL4071554)
Affinity DataIC50: 313nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501632(CHEMBL4094214)
Affinity DataIC50: 500nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501629(CHEMBL4070768)
Affinity DataIC50: 563nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501634(CHEMBL4098586)
Affinity DataIC50: 717nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501627(CHEMBL4085570)
Affinity DataIC50: 814nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501625(CHEMBL4101049)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501635(CHEMBL4083075)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501626(CHEMBL4072603)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50236230(ursodeoxy cholic acid | 2-((R)-4-((3R,5S,7S,8R,9S,...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501622(CHEMBL4097881)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501621(CHEMBL4096938)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501620(CHEMBL4078911)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501628(CHEMBL4064007)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed