Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50048292
TargetAcyl-protein thioesterase 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM207992(ML349)
Affinity DataKi:  120nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50212216(CHEMBL3944678)
Affinity DataKi:  1.10E+3nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50212217(CHEMBL3917640)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50212218(CHEMBL3974081)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  82nMAssay Description:Inhibition of full length human His6/GST-tagged NQO2 expressed in Escherichia coli Tuner(DE3)pLysS using menadione as substrate and CCHP as co-substr...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataIC50:  381nMAssay Description:Inhibition of full length human His6/GST-tagged NQO2 expressed in Escherichia coli Tuner(DE3)pLysS using menadione as substrate and CCHP as co-substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM207992(ML349)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of fluorescein-labeled ML349 binding to HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) after 30 mins by flu...More data for this Ligand-Target Pair
TargetPyridoxal kinase(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM207992(ML349)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fluorescein-labeled ML349 binding to HEK293T cells-derived His-tagged PDXK expressed in Escherichia coli BL21(DE3) after 30 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50212216(CHEMBL3944678)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fluorescein-labeled ML349 binding to HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) after 30 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPyridoxal kinase(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50212216(CHEMBL3944678)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of fluorescein-labeled ML349 binding to HEK293T cells-derived His-tagged PDXK expressed in Escherichia coli BL21(DE3) after 30 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed