Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50049207
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50236558(CHEMBL4101903)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human FXR expressed in COS1 cells assessed as inhibition of CDCA-induced receptor activation after 2 days by luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50236555(CHEMBL4089646)
Affinity DataIC50: 3.58E+3nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50236562(CHEMBL4067798)
Affinity DataIC50: 3.87E+3nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50236556(CHEMBL4094011)
Affinity DataIC50: 3.98E+3nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM235634((E)-1-(2,4-dihydroxyphenyl)-3-(2-methoxyphenyl)-2-...)
Affinity DataIC50: 4.29E+3nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50236554(CHEMBL4105380)
Affinity DataIC50: 8.11E+3nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50360513(CHEMBL573523)
Affinity DataIC50: 1.51E+4nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50236561(CHEMBL4070048)
Affinity DataIC50: 1.53E+4nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50236560(CHEMBL4083985)
Affinity DataIC50: 1.62E+4nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50236552(CHEMBL4067328)
Affinity DataIC50: 1.73E+4nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50236553(CHEMBL4104940)
Affinity DataIC50: 1.82E+4nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50236559(CHEMBL4067658)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50236557(CHEMBL4087479)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed