Compile Data Set for Download or QSAR
Report error Found 81 Enz. Inhib. hit(s) with all data for entry = 50049042
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288531((1R,3R,5S,6r)-3-[8- amino-1-(4-{[4- (trifluorometh...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288463(4-(8-amino-1-(2- fluoro-4-((4- (trifluoromethyl) p...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233382(CHEMBL4074833)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233392(CHEMBL4068131)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288560(4-[8-amino-1-(4-{[4- (trifluoromethyl) pyridin-2- ...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233389(CHEMBL4070865)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288473((1S,3R)-3-[8-amino-1- (4-{[4- (trifluoromethyl) py...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233391(CHEMBL4081444)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233386(CHEMBL4100424)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233388(CHEMBL4081452)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM267790(4-(8-amino-3-{(3R,6S)-6-methyl-1-[(3-methyloxetan-...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288564(4-[8-amino-1-(2- ethoxy-4-{[4- (trifluoromethyl) p...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288308(US10087188, Example 1 | US10087188, Example 6)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233393(CHEMBL4096195)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288492((1R,2R,5R)-5-[8- amino-1-(4-{[4- (trifluoromethyl)...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288429(3-[8-amino-1-(4-{[4- (trifluoromethyl) pyridin-2- ...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288550(cis-4-[8-amino-1-(4- {[4- (trifluoromethyl) pyridi...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233396(CHEMBL4059483)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233385(CHEMBL4062247)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233387(CHEMBL4082411)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288374(US10087188, Example 13)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288546((1S,3R)-3-[8-amino-1- (4-{[4- (trifluoromethyl) py...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233394(CHEMBL4079697)
Affinity DataIC50: 1nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288439((1S,3R)-3-[8-amino-1- (4-{[4- (trifluoromethyl) py...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233384(CHEMBL4105560)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233390(CHEMBL4097968)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288431((1S,3R)-3-[8-amino-1- (4-{[4- (trifluoromethyl) py...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233395(CHEMBL4090257)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288482((1S,3R)-3-[8-amino-1- (4-{[4- (trifluoromethyl) py...)
Affinity DataIC50: 3nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM267790(4-(8-amino-3-{(3R,6S)-6-methyl-1-[(3-methyloxetan-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233383(CHEMBL4095276)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288560(4-[8-amino-1-(4-{[4- (trifluoromethyl) pyridin-2- ...)
Affinity DataIC50: 5nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233387(CHEMBL4082411)
Affinity DataIC50: 5nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233391(CHEMBL4081444)
Affinity DataIC50: 6nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288473((1S,3R)-3-[8-amino-1- (4-{[4- (trifluoromethyl) py...)
Affinity DataIC50: 8nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233392(CHEMBL4068131)
Affinity DataIC50: 9nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288531((1R,3R,5S,6r)-3-[8- amino-1-(4-{[4- (trifluorometh...)
Affinity DataIC50: 11nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233389(CHEMBL4070865)
Affinity DataIC50: 17nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233394(CHEMBL4079697)
Affinity DataIC50: 17nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233386(CHEMBL4100424)
Affinity DataIC50: 17nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233382(CHEMBL4074833)
Affinity DataIC50: 18nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233393(CHEMBL4096195)
Affinity DataIC50: 20nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233388(CHEMBL4081452)
Affinity DataIC50: 21nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288492((1R,2R,5R)-5-[8- amino-1-(4-{[4- (trifluoromethyl)...)
Affinity DataIC50: 22nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288564(4-[8-amino-1-(2- ethoxy-4-{[4- (trifluoromethyl) p...)
Affinity DataIC50: 24nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288546((1S,3R)-3-[8-amino-1- (4-{[4- (trifluoromethyl) py...)
Affinity DataIC50: 26nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288439((1S,3R)-3-[8-amino-1- (4-{[4- (trifluoromethyl) py...)
Affinity DataIC50: 27nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50233396(CHEMBL4059483)
Affinity DataIC50: 37nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288463(4-(8-amino-1-(2- fluoro-4-((4- (trifluoromethyl) p...)
Affinity DataIC50: 49nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM288431((1S,3R)-3-[8-amino-1- (4-{[4- (trifluoromethyl) py...)
Affinity DataIC50: 62nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2019
Entry Details Article
PubMed
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