Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50049227
TargetProstaglandin G/H synthase 2(Human)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50236985(CHEMBL4098600)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50236980(CHEMBL4097499)
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50236981(CHEMBL4086580)
Affinity DataIC50: 670nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50236984(CHEMBL4069250)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.81E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by ADHP pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50236985(CHEMBL4098600)
Affinity DataIC50: 2.96E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by ADHP pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50236981(CHEMBL4086580)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by ADHP pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50236980(CHEMBL4097499)
Affinity DataIC50: 6.13E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by ADHP pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50236984(CHEMBL4069250)
Affinity DataIC50: 6.88E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by ADHP pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2019
Entry Details Article
PubMed