Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50000751
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50403016(CHEMBL2207845)
Affinity DataIC50: 5nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to myc-tagged human Plk1 PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260121(CHEMBL4068949)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to myc-tagged human Plk1 PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260122(CHEMBL4092848)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to myc-tagged human Plk1 PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50194933(CHEMBL3956625)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to myc-tagged human Plk1 PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260124(CHEMBL4065187)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to myc-tagged human Plk1 PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260123(CHEMBL4080819)
Affinity DataIC50: 11nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to myc-tagged human Plk1 PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50194933(CHEMBL3956625)
Affinity DataIC50: 127nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to myc-tagged full-length human Plk1 expressed in HEK-293T cells incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50403016(CHEMBL2207845)
Affinity DataIC50: 130nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to myc-tagged Plk2 (unknown origin) PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260124(CHEMBL4065187)
Affinity DataIC50: 152nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to myc-tagged full-length human Plk1 expressed in HEK-293T cells incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50403016(CHEMBL2207845)
Affinity DataIC50: 181nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to myc-tagged full-length human Plk1 expressed in HEK-293T cells incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260121(CHEMBL4068949)
Affinity DataIC50: 188nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to myc-tagged full-length human Plk1 expressed in HEK-293T cells incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260122(CHEMBL4092848)
Affinity DataIC50: 218nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to myc-tagged full-length human Plk1 expressed in HEK-293T cells incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260124(CHEMBL4065187)
Affinity DataIC50: 250nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to myc-tagged Plk2 (unknown origin) PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50403016(CHEMBL2207845)
Affinity DataIC50: 280nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to myc-tagged Plk3 (unknown origin) PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence pola...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50194933(CHEMBL3956625)
Affinity DataIC50: 290nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to myc-tagged Plk2 (unknown origin) PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50403017(CHEMBL2207846)
Affinity DataIC50: 300nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to myc-tagged full-length human Plk1 expressed in HEK-293T cells incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260122(CHEMBL4092848)
Affinity DataIC50: 310nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to myc-tagged Plk2 (unknown origin) PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260123(CHEMBL4080819)
Affinity DataIC50: 862nMAssay Description:Inhibition of Biotin-Ahx-PMQS(pT)PLN-NH2 binding to myc-tagged full-length human Plk1 expressed in HEK-293T cells incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260124(CHEMBL4065187)
Affinity DataIC50: 920nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to myc-tagged Plk3 (unknown origin) PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence pola...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260122(CHEMBL4092848)
Affinity DataIC50: 960nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to myc-tagged Plk3 (unknown origin) PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence pola...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50194933(CHEMBL3956625)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to myc-tagged Plk3 (unknown origin) PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence pola...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260121(CHEMBL4068949)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to myc-tagged Plk3 (unknown origin) PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence pola...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260121(CHEMBL4068949)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to myc-tagged Plk2 (unknown origin) PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260123(CHEMBL4080819)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to myc-tagged Plk2 (unknown origin) PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence pol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50260123(CHEMBL4080819)
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to myc-tagged Plk3 (unknown origin) PBD expressed in HEK-293T cells incubated for 1 hr by fluorescence pola...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed