Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50000170
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241952(CHEMBL4099528)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241967(CHEMBL4087626)
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241961(CHEMBL4081514)
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241957(CHEMBL4100650)
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241953(CHEMBL4091792)
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241941(CHEMBL4103080)
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241954(CHEMBL4082655)
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241941(CHEMBL4103080)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098793(CHEMBL3593342)
Affinity DataIC50: 2.70E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241952(CHEMBL4099528)
Affinity DataIC50: 2.70E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241961(CHEMBL4081514)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241940(CHEMBL4078805)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241957(CHEMBL4100650)
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241954(CHEMBL4082655)
Affinity DataIC50: 4.20E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50011360(CHEMBL3260990)
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241958(CHEMBL4063555)
Affinity DataIC50: 4.50E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241953(CHEMBL4091792)
Affinity DataIC50: 4.60E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241958(CHEMBL4063555)
Affinity DataIC50: 5.60E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241966(CHEMBL4092921)
Affinity DataIC50: 5.60E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241959(CHEMBL4097097)
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241966(CHEMBL4092921)
Affinity DataIC50: 7.00E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241940(CHEMBL4078805)
Affinity DataIC50: 7.20E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241967(CHEMBL4087626)
Affinity DataIC50: 7.30E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241964(CHEMBL4074930)
Affinity DataIC50: 7.80E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241960(CHEMBL4061233)
Affinity DataIC50: 8.50E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241951(CHEMBL4092801)
Affinity DataIC50: 8.60E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241948(CHEMBL4067920)
Affinity DataIC50: 9.00E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241973(CHEMBL4086657)
Affinity DataIC50: 9.50E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241962(CHEMBL4072161)
Affinity DataIC50: 9.90E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241935(CHEMBL4066321)
Affinity DataIC50: 1.02E+4nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241950(CHEMBL4095327)
Affinity DataIC50: 1.02E+4nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50011360(CHEMBL3260990)
Affinity DataIC50: 1.08E+4nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241963(CHEMBL4085177)
Affinity DataIC50: 1.14E+4nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241971(CHEMBL4101618)
Affinity DataIC50: 1.14E+4nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241947(CHEMBL4105509)
Affinity DataIC50: 1.19E+4nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241972(CHEMBL4102135)
Affinity DataIC50: 1.27E+4nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241968(CHEMBL4069895)
Affinity DataIC50: 1.31E+4nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241970(CHEMBL4070928)
Affinity DataIC50: 1.32E+4nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241969(CHEMBL4089389)
Affinity DataIC50: 1.89E+4nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241936(CHEMBL4084165)
Affinity DataIC50: 3.86E+4nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241965(CHEMBL4093887)
Affinity DataIC50: 7.76E+4nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241942(CHEMBL3593466)
Affinity DataIC50: 1.50E+5nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed