Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50048962
LigandChemical structure of BindingDB Monomer ID 50231814BDBM50231814(CHEMBL4078870 | US11725000, Compound 289)
Affinity DataEC50:  0.230nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing tBid assessed as reduction in apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231814BDBM50231814(CHEMBL4078870 | US11725000, Compound 289)
Affinity DataEC50:  0.420nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231783BDBM50231783(CHEMBL4078220 | US11725000, Compound 155)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231789BDBM50231789(CHEMBL4091379 | US11725000, Compound 127)
Affinity DataEC50:  25nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231785BDBM50231785(CHEMBL4064603 | US11725000, Compound 152)
Affinity DataEC50:  27nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231795BDBM50231795(CHEMBL4070501 | US11725000, Compound 109)
Affinity DataEC50:  57nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231821BDBM50231821(CHEMBL4061878 | US11725000, Compound 106)
Affinity DataEC50:  66nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231820BDBM50231820(CHEMBL4092330 | US11725000, Compound 113)
Affinity DataEC50:  69nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231793BDBM50231793(CHEMBL4082074 | US11725000, Compound 110)
Affinity DataEC50:  94nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231794BDBM50231794(CHEMBL4071549 | US11725000, Compound 112)
Affinity DataEC50:  110nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231817BDBM50231817(CHEMBL4086114 | US11725000, Compound 151)
Affinity DataEC50:  164nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231787BDBM50231787(CHEMBL4093871 | US11725000, Compound 143)
Affinity DataEC50:  216nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231788BDBM50231788(CHEMBL4083596 | US11725000, Compound 146)
Affinity DataEC50:  253nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231797BDBM50231797(CHEMBL4089942 | US11725000, Compound 105)
Affinity DataEC50:  257nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231786BDBM50231786(CHEMBL4073188 | US11725000, Compound 144)
Affinity DataEC50:  282nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231818BDBM50231818(CHEMBL4101603 | US11725000, Compound 147)
Affinity DataEC50:  364nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 31068BDBM31068(MLS000044645 | cid_3245258 | 2-methylsulfonyl-4-th...)
Affinity DataEC50:  749nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231819BDBM50231819(CHEMBL4101046 | US11725000, Compound 122)
Affinity DataEC50:  817nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231809BDBM50231809(CHEMBL4070722 | US11725000, Compound 29)
Affinity DataEC50:  1.14E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231798BDBM50231798(CHEMBL4063455 | US11725000, Compound 104)
Affinity DataEC50:  1.14E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231799BDBM50231799(CHEMBL4085084 | US11725000, Compound 103)
Affinity DataEC50:  1.16E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231810BDBM50231810(CHEMBL4097841 | US11725000, Compound 3)
Affinity DataEC50:  1.43E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231825BDBM50231825(CHEMBL4090123 | US11725000, Compound 26)
Affinity DataEC50:  1.59E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231796BDBM50231796(CHEMBL4097672 | US11725000, Compound 108)
Affinity DataEC50:  1.82E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 31063BDBM31063(MLS000044644 | 2-methylsulfonyl-4-phenyl-6-(triflu...)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231803BDBM50231803(CHEMBL4096202 | US11725000, Compound 47)
Affinity DataEC50:  3.49E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231790BDBM50231790(CHEMBL4063532 | US11725000, Compound 119)
Affinity DataEC50:  3.49E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231811BDBM50231811(CHEMBL4086039 | US11725000, Compound 60)
Affinity DataEC50:  3.52E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231815BDBM50231815(CHEMBL4103147 | US11725000, Compound Hit)
Affinity DataEC50:  4.00E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231791BDBM50231791(CHEMBL4074296 | US11725000, Compound 118)
Affinity DataEC50:  4.06E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231808BDBM50231808(CHEMBL4062092)
Affinity DataEC50:  4.21E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231792BDBM50231792(CHEMBL4100077 | US11725000, Compound 120)
Affinity DataEC50:  4.48E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231802BDBM50231802(CHEMBL4078150 | US11725000, Compound 48)
Affinity DataEC50:  6.36E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231804BDBM50231804(CHEMBL4104624 | US11725000, Compound 46)
Affinity DataEC50:  6.64E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231812BDBM50231812(CHEMBL4103961 | US11725000, Compound 58)
Affinity DataEC50:  7.03E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231800BDBM50231800(CHEMBL4088482 | US11725000, Compound 73)
Affinity DataEC50:  8.76E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231801BDBM50231801(CHEMBL4104840 | US11725000, Compound 69)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231816BDBM50231816(CHEMBL4102499 | US11725000, Compound 158)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231807BDBM50231807(CHEMBL4068001 | US11725000, Compound 34)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231806BDBM50231806(CHEMBL4105576 | US11725000, Compound 37)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231824BDBM50231824(CHEMBL4089190 | US11725000, Compound 41)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231822BDBM50231822(CHEMBL4067221 | US11725000, Compound 99)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231805BDBM50231805(CHEMBL4081324)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231823BDBM50231823(CHEMBL4080611 | US11725000, Compound 61)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed