Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50006665
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Beijing Institute of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50501724(CHEMBL4095512)
Affinity DataEC50:  2.90nMAssay Description:Inhibition of rilpivirine-resistant HIV1 NL4-3 reverse transcriptase E138K mutant infected in human TZM-b1 cells after 2 days by bright Glo-luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Beijing Institute of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM222178(Rilpivirine)
Affinity DataEC50:  3.60nMAssay Description:Inhibition of rilpivirine-resistant HIV1 NL4-3 reverse transcriptase E138K mutant infected in human TZM-b1 cells after 2 days by bright Glo-luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Beijing Institute of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50501727(CHEMBL4075078)
Affinity DataEC50:  4.60nMAssay Description:Inhibition of rilpivirine-resistant HIV1 NL4-3 reverse transcriptase E138K mutant infected in human TZM-b1 cells after 2 days by bright Glo-luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Beijing Institute of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50501725(CHEMBL4092910)
Affinity DataEC50:  8.5nMAssay Description:Inhibition of rilpivirine-resistant HIV1 NL4-3 reverse transcriptase E138K mutant infected in human TZM-b1 cells after 2 days by bright Glo-luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Beijing Institute of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50501726(CHEMBL4085171)
Affinity DataEC50:  8.70nMAssay Description:Inhibition of rilpivirine-resistant HIV1 NL4-3 reverse transcriptase E138K mutant infected in human TZM-b1 cells after 2 days by bright Glo-luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Beijing Institute of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50501728(CHEMBL4072151)
Affinity DataEC50:  23nMAssay Description:Inhibition of rilpivirine-resistant HIV1 NL4-3 reverse transcriptase E138K mutant infected in human TZM-b1 cells after 2 days by bright Glo-luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed