Compile Data Set for Download or QSAR
Report error Found 91 Enz. Inhib. hit(s) with all data for entry = 50000566
LigandPNGBDBM50253706(CHEMBL4083927)
Affinity DataKd:  0.541nMAssay Description:Binding affinity to recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253706(CHEMBL4083927)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253676(CHEMBL4087760)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253759(CHEMBL4078941)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253762(CHEMBL4098392)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253708(CHEMBL4070822)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253702(CHEMBL4080673)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253753(CHEMBL4062209)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253677(CHEMBL4095460)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253706(CHEMBL4083927)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253753(CHEMBL4062209)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253703(CHEMBL4078031)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253674(CHEMBL4084945)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253668(CHEMBL4086790)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253698(CHEMBL4068071)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253672(CHEMBL4091279)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253675(CHEMBL4080367)
Affinity DataKd:  2.80nMAssay Description:Binding affinity to recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253699(CHEMBL4103214)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253700(CHEMBL4065361)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK1 catalytic domain (1 to 477 residues) expressed in baculovirus expression system using Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253761(CHEMBL4081417)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253762(CHEMBL4098392)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253670(CHEMBL4096077)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253707(CHEMBL4091694)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253702(CHEMBL4080673)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253760(CHEMBL4105646)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253675(CHEMBL4080367)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253669(CHEMBL4061122)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253752(CHEMBL4099435)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253668(CHEMBL4086790)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK1 catalytic domain (1 to 477 residues) expressed in baculovirus expression system using Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetCell division cycle 7-related protein kinase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253702(CHEMBL4080673)
Affinity DataIC50: 67nMAssay Description:Inhibition of Cdc7 in human HeLa cells assessed as reduction in MCM2 phosphorylation at ser40 residues after 7 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253702(CHEMBL4080673)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253673(CHEMBL4063842)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253762(CHEMBL4098392)
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253700(CHEMBL4065361)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253706(CHEMBL4083927)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK1 catalytic domain (1 to 477 residues) expressed in baculovirus expression system using Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253701(CHEMBL4073971)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253753(CHEMBL4062209)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253675(CHEMBL4080367)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253759(CHEMBL4078941)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK1 catalytic domain (1 to 477 residues) expressed in baculovirus expression system using Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253760(CHEMBL4105646)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK1 catalytic domain (1 to 477 residues) expressed in baculovirus expression system using Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253675(CHEMBL4080367)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK1 catalytic domain (1 to 477 residues) expressed in baculovirus expression system using Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253762(CHEMBL4098392)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253706(CHEMBL4083927)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253703(CHEMBL4078031)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK1 catalytic domain (1 to 477 residues) expressed in baculovirus expression system using Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetCell division cycle 7-related protein kinase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253706(CHEMBL4083927)
Affinity DataIC50: 250nMAssay Description:Inhibition of Cdc7 in human HeLa cells assessed as reduction in MCM2 phosphorylation at ser40 residues after 7 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253753(CHEMBL4062209)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK1 catalytic domain (1 to 477 residues) expressed in baculovirus expression system using Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253671(CHEMBL4062454)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
LigandPNGBDBM50253675(CHEMBL4080367)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetCell division cycle 7-related protein kinase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253753(CHEMBL4062209)
Affinity DataIC50: 350nMAssay Description:Inhibition of Cdc7 in human HeLa cells assessed as reduction in MCM2 phosphorylation at ser40 residues after 7 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253708(CHEMBL4070822)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK1 catalytic domain (1 to 477 residues) expressed in baculovirus expression system using Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
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