Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50000047
TargetToll-like receptor 3(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50239681(CHEMBL4074408)
Affinity DataEC50:  4.80E+3nMAssay Description:Agonist activity at human TLR3 expressed in HEK293 cells assessed as induction of NF-kB activation-mediated SEAP production after 24 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetToll-like receptor 9(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50239681(CHEMBL4074408)
Affinity DataEC50:  5.66E+3nMAssay Description:Agonist activity at human TLR9 expressed in HEK293 cells assessed as induction of NF-kB activation-mediated SEAP production after 24 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50239681(CHEMBL4074408)
Affinity DataEC50:  1.35E+4nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NF-kB activation-mediated SEAP production after 24 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetToll-like receptor 3(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50239682(CHEMBL4105063)
Affinity DataEC50:  2.23E+4nMAssay Description:Agonist activity at human TLR3 expressed in HEK293 cells assessed as induction of NF-kB activation-mediated SEAP production after 24 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetToll-like receptor 3(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50239680(CHEMBL4064228)
Affinity DataEC50:  4.25E+4nMAssay Description:Agonist activity at human TLR3 expressed in HEK293 cells assessed as induction of NF-kB activation-mediated SEAP production after 24 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50239681(CHEMBL4074408)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells assessed as induction of NF-kB activation-mediated SEAP production after 24 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50239681(CHEMBL4074408)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 cells assessed as induction of NF-kB activation-mediated SEAP production after 24 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetToll-like receptor 5(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50239681(CHEMBL4074408)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TLR5 expressed in HEK293 cells assessed as induction of NF-kB activation-mediated SEAP production after 24 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50239681(CHEMBL4074408)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kB activation-mediated SEAP production after 24 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed