Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50001036
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268142BDBM50268142(CHEMBL4098313)
Affinity DataKi:  100nMAssay Description:Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268140BDBM50268140(CHEMBL4061954)
Affinity DataKi:  250nMAssay Description:Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268154BDBM50268154(CHEMBL4090466)
Affinity DataKi:  300nMAssay Description:Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268138BDBM50268138(CHEMBL4066860)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268141BDBM50268141(CHEMBL4071268)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268153BDBM50268153(CHEMBL4068620)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268136BDBM50268136(CHEMBL4075237)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268143BDBM50268143(CHEMBL4090584)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268139BDBM50268139(CHEMBL4077791)
Affinity DataKi:  9.70E+3nMAssay Description:Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268137BDBM50268137(CHEMBL4076465)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268152BDBM50268152(CHEMBL4094810)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of N-terminal hexa-histidine-tagged human HGPRT using PRib-PP as substrate in presence of guanine by Hanes plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed