TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Csir - Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir - Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:Inhibition of human MDR1 expressed in pig LLC-PK1 cells assessed as reduction in calcein-AM efflux preincubated for 30 mins followed by calcein-AM ad...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Csir - Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir - Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of human MDR1 expressed in pig LLC-PK1 cells assessed as reduction in [3H]vinblastine efflux after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Csir - Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir - Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of [125I]IAAP labeling to human MDR1 expressed in baculovirus infected insect cell membranes by electrophoresis methodMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Csir - Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir - Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human MDR1 ATPase activity expressed in baculovirus infected insect cells preincubated for 30 mins followed by ATP addition measured af...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Csir - Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir - Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Displacement of 8-azido[alpha-32P]ATP from human MDR1 expressed in baculovirus infected insect cell membranes by phosphorimaging methodMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Csir - Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir - Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of BCRP (unknown origin)More data for this Ligand-Target Pair