Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50001091
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269302BDBM50269302(CHEMBL4060515)
Affinity DataIC50: 276nMAssay Description:Inhibition of human mPGES-1 expressed in 293-F cells using PGH2 as substrate preincubated for 15 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269300BDBM50269300(CHEMBL4077049)
Affinity DataIC50: 284nMAssay Description:Inhibition of human mPGES-1 expressed in 293-F cells using PGH2 as substrate preincubated for 15 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269301BDBM50269301(CIBA-1906 | Thiambutosine)
Affinity DataIC50: 370nMAssay Description:Inhibition of human mPGES-1 expressed in 293-F cells using PGH2 as substrate preincubated for 15 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269299BDBM50269299(CHEMBL4077072)
Affinity DataIC50: 439nMAssay Description:Inhibition of human mPGES-1 expressed in 293-F cells using PGH2 as substrate preincubated for 15 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269303BDBM50269303(CHEMBL4071915)
Affinity DataIC50: 664nMAssay Description:Inhibition of human mPGES-1 expressed in 293-F cells using PGH2 as substrate preincubated for 15 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269304BDBM50269304(CHEMBL4093446)
Affinity DataIC50: 889nMAssay Description:Inhibition of human mPGES-1 expressed in 293-F cells using PGH2 as substrate preincubated for 15 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269305BDBM50269305(CHEMBL1970663)
Affinity DataIC50: 917nMAssay Description:Inhibition of human mPGES-1 expressed in 293-F cells using PGH2 as substrate preincubated for 15 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details Article
PubMed