Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50001120
LigandChemical structure of BindingDB Monomer ID 50269660BDBM50269660(CHEMBL4067554)
Affinity DataEC50:  11nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269663BDBM50269663(CHEMBL4076583)
Affinity DataEC50:  28nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269664BDBM50269664(CHEMBL4076657)
Affinity DataEC50:  54nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269681BDBM50269681(CHEMBL4077565)
Affinity DataEC50:  66nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269669BDBM50269669(CHEMBL4065256)
Affinity DataEC50:  82nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269682BDBM50269682(CHEMBL4076994)
Affinity DataEC50:  86nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269676BDBM50269676(CHEMBL4074380)
Affinity DataEC50:  87nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269668BDBM50269668(CHEMBL4073357)
Affinity DataEC50:  138nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269670BDBM50269670(CHEMBL4072058)
Affinity DataEC50:  153nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269683BDBM50269683(CHEMBL4084074)
Affinity DataEC50:  329nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269659BDBM50269659(CHEMBL4069984)
Affinity DataEC50:  332nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269678BDBM50269678(CHEMBL4092140)
Affinity DataEC50:  583nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269671BDBM50269671(CHEMBL4084423)
Affinity DataEC50:  1.13E+3nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269680BDBM50269680(CHEMBL4073694)
Affinity DataEC50:  1.15E+3nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269684BDBM50269684(CHEMBL4062360)
Affinity DataEC50:  3.45E+3nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269675BDBM50269675(CHEMBL4087839)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269673BDBM50269673(CHEMBL1909927)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269674BDBM50269674(CHEMBL4065676)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269672BDBM50269672(CHEMBL463097)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50318482BDBM50318482(CHEMBL470670 | l-menthol | (-)-menthol | MENTHOL |...)
Affinity DataEC50:  1.01E+4nMAssay Description:Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50269659BDBM50269659(CHEMBL4069984)
Affinity DataEC50:  1.91E+4nMAssay Description:Agonist activity at recombinant human TRPA1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for 5 mins by Fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50318482BDBM50318482(CHEMBL470670 | l-menthol | (-)-menthol | MENTHOL |...)
Affinity DataEC50:  9.60E+4nMAssay Description:Agonist activity at recombinant human TRPA1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for 5 mins by Fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed