TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Iota Pharmaceuticals
Curated by ChEMBL
Iota Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.10E+5nMAssay Description:Inhibition of N-terminal 6xHis-tagged PDE10A (unknown origin) expressed in BL21 (DE3) RIL cells using 3',5'-cGMP as substrate by microcalorimetric as...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Iota Pharmaceuticals
Curated by ChEMBL
Iota Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of human PDE4D catalytic domain using [3H]-cAMP as substrate after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair