Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50000123
TargetHeat shock protein HSP 90-alpha(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20800BDBM20800(CHEMBL467399 | 6-chloro-9-[(4-methoxy-3,5-dimethyl...)
Affinity DataIC50: 52nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240873BDBM50240873(CHEMBL4068596)
Affinity DataIC50: 79nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180302BDBM50180302(8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPRO...)
Affinity DataIC50: 89nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240875BDBM50240875(CHEMBL4080323)
Affinity DataIC50: 97nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240875BDBM50240875(CHEMBL4080323)
Affinity DataIC50: 138nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180302BDBM50180302(8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPRO...)
Affinity DataIC50: 257nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20800BDBM20800(CHEMBL467399 | 6-chloro-9-[(4-methoxy-3,5-dimethyl...)
Affinity DataIC50: 535nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240873BDBM50240873(CHEMBL4068596)
Affinity DataIC50: 698nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240872BDBM50240872(CHEMBL4095912)
Affinity DataIC50: 6.34E+3nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240874BDBM50240874(CHEMBL4079410)
Affinity DataIC50: 8.43E+3nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240872BDBM50240872(CHEMBL4095912)
Affinity DataIC50: 8.93E+3nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240874BDBM50240874(CHEMBL4079410)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240871BDBM50240871(CHEMBL4103668)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240871BDBM50240871(CHEMBL4103668)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed