Report error Found 139 Enz. Inhib. hit(s) with all data for entry = 50019108
Affinity DataKi: 0.0620nMAssay Description:Binding affinity to Abl (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity to Abl (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity to Abl (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity to Abl (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Human)
Universita Degli Studi Di Palermo
Curated by ChEMBL
Universita Degli Studi Di Palermo
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human GST-tagged IRAK4 incubated for 30 mins in presence of ATP by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SYK using 5-Fluo-Ahx-GAPDYENLQELNKK-Amid as substrate in presence of ATP by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SYK using 5-Fluo-Ahx-GAPDYENLQELNKK-Amid as substrate in presence of ATP by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SYK using 5-Fluo-Ahx-GAPDYENLQELNKK-Amid as substrate in presence of ATP by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SYK using 5-Fluo-Ahx-GAPDYENLQELNKK-Amid as substrate in presence of ATP by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SYK using 5-Fluo-Ahx-GAPDYENLQELNKK-Amid as substrate in presence of ATP by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SYK using 5-Fluo-Ahx-GAPDYENLQELNKK-Amid as substrate in presence of ATP by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SYK using 5-Fluo-Ahx-GAPDYENLQELNKK-Amid as substrate in presence of ATP by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SYK using 5-Fluo-Ahx-GAPDYENLQELNKK-Amid as substrate in presence of ATP by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SYK using 5-Fluo-Ahx-GAPDYENLQELNKK-Amid as substrate in presence of ATP by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SYK using 5-Fluo-Ahx-GAPDYENLQELNKK-Amid as substrate in presence of ATP by microfluidic mobility shift assayMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Human)
Universita Degli Studi Di Palermo
Curated by ChEMBL
Universita Degli Studi Di Palermo
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human GST-tagged IRAK4 incubated for 30 mins in presence of ATP by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity to Abl (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of BMI1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity to Abl-T315I mutant (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity to Abl (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity to Abl (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity to Abl (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity to Abl (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Human)
Universita Degli Studi Di Palermo
Curated by ChEMBL
Universita Degli Studi Di Palermo
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human GST-tagged IRAK4 incubated for 30 mins in presence of ATP by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Binding affinity to Abl (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Binding affinity to Abl (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair










3D Structure (crystal)





































