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Found 23 Enz. Inhib. hit(s) with all data for entry = 50000837
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261565(CHEMBL4098239)
Affinity DataIC50:  7nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261578(CHEMBL4085932)
Affinity DataIC50:  65nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261559(CHEMBL4067116)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261561(CHEMBL4075710)
Affinity DataIC50:  110nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261577(CHEMBL4077445)
Affinity DataIC50:  120nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261563(CHEMBL4089618)
Affinity DataIC50:  129nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261562(CHEMBL4068479)
Affinity DataIC50:  198nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261581(CHEMBL4086863)
Affinity DataIC50:  202nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261575(CHEMBL4102621)
Affinity DataIC50:  210nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261580(CHEMBL4100191)
Affinity DataIC50:  232nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261583(CHEMBL4081744)
Affinity DataIC50:  250nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261570(CHEMBL4071193)
Affinity DataIC50:  250nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261579(CHEMBL4064401)
Affinity DataIC50:  250nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261585(CHEMBL4073866)
Affinity DataIC50:  290nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261582(CHEMBL4083620)
Affinity DataIC50:  300nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  309nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261560(CHEMBL4094577)
Affinity DataIC50:  325nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261564(CHEMBL4059816)
Affinity DataIC50:  500nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261573(CHEMBL4098852)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261576(CHEMBL4078353)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261584(CHEMBL4062557)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  2.30nMAssay Description:Binding affinity to ER (unknown origin) expressed in UAS-bla GripTite 293 cells by Select screen competitive binding assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261561(CHEMBL4075710)
Affinity DataEC50:  432nMAssay Description:Binding affinity to ER (unknown origin) expressed in UAS-bla GripTite 293 cells by Select screen competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed