Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50000845
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261674(CHEMBL4086045)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261669(CHEMBL4084641)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261667(CHEMBL4101097)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261675(CHEMBL4060025)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261664(CHEMBL4067601)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261666(CHEMBL4100132)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261693(CHEMBL4072950)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261665(CHEMBL4082125)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261691(CHEMBL4094738)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261696(CHEMBL4074358)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261695(CHEMBL4092377)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261661(CHEMBL4071600)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261661(CHEMBL4071600)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261692(CHEMBL4068107)
Affinity DataEC50:  79nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261660(CHEMBL4070562)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261668(CHEMBL4062970)
Affinity DataEC50:  126nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261663(CHEMBL4079960)
Affinity DataEC50:  158nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261661(CHEMBL4071600)
Affinity DataEC50:  251nMAssay Description:Agonist activity at mouse CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261661(CHEMBL4071600)
Affinity DataEC50:  316nMAssay Description:Agonist activity at rat CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261694(CHEMBL4097717)
Affinity DataEC50:  398nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261690(CHEMBL4091950)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261697(CHEMBL4069946)
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261662(CHEMBL4076239)
Affinity DataEC50:  3.16E+3nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed