Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50002552
TargetApoptosis regulator Bcl-2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM356652(trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...)
Affinity DataKi: <0.0100nMAssay Description:Inhibition of Bcl2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKi: <0.0100nMAssay Description:Inhibition of Bcl2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKi:  0.0440nMAssay Description:Inhibition of Bcl2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKi:  0.0550nMAssay Description:Inhibition of Bcl-xL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBcl-2-like protein 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <1nMAssay Description:Inhibition of Bcl-xL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <1nMAssay Description:Inhibition of Bcl2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM356652(trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...)
Affinity DataKi:  14nMAssay Description:Inhibition of Bcl-xL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKi:  48nMAssay Description:Inhibition of Bcl-xL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed