Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50002069
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50002338(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]quinuclidinyl benzilate (QNB) from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50002338(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]haloperidol from Dopamine receptor D2 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50002338(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]WB-4101 from alpha-1 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50002338(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Affinity DataIC50: 60nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor as antagonism of serotonin-induced contractions in rat jugular veinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50002338(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]cis-flupenthixol from Dopamine receptor D1 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50002338(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]clonidine from alpha-2 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50002338(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Affinity DataIC50: 8.70E+3nMAssay Description:Displacement of [3H]-5-HT from serotonin-1 neurotransmitter receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]WB-4101 from alpha-1 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]clonidine from alpha-2 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]quinuclidinyl benzilate(QNB) from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DHA (Dihydroalprenolol) from beta-1 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]5-HT from serotonin-1 neurotransmitter receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]spiroperidol from 5-hydroxytryptamine 2 receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nitrendipine from L-type [Ca2+] channel of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]haloperidol from Dopamine receptor D2 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50002338(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DHA (Dihydroalprenolol) from beta-1 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50002338(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DHA (Dihydroalprenolol) from beta-2 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]cis-flupenthixol from Dopamine receptor D1 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DHA (Dihydroalprenolol) from beta-2 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50002338(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-CHA (N6-Cyclohexyl adenosine) from adenosine A1 receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]CHA (N6-Cyclohexyl adenosine) from adenosine A1 receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed