Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50000467
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50: 60nMAssay Description:Allosteric inhibition of 2P-IRS-1 stimulated wild type SHP2 (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of CDC25A (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 3.12E+4nMAssay Description:Inhibition of PTP1B (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 3.46E+4nMAssay Description:Inhibition of SHP1 (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VHR (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3 (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LMW-PTP (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50250916(CHEMBL4088271)
Affinity DataIC50: 1.00E+5nMAssay Description:Allosteric inhibition of 2P-IRS-1 stimulated wild type SHP2 (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed