Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50000334
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50125265(N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246881(CHEMBL4076292)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246879(CHEMBL4066748)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246900(CHEMBL4060770)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246880(CHEMBL4088042)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246878(CHEMBL4088985)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246906(CHEMBL4076690)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246897(CHEMBL4070470)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246901(CHEMBL4074539)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246907(CHEMBL4099132)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246891(CHEMBL4097263)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246882(CHEMBL4096131)
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246898(CHEMBL4091394)
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246893(CHEMBL4104461)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246892(CHEMBL4075421)
Affinity DataIC50: 152nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246905(CHEMBL4086960)
Affinity DataIC50: 222nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246876(CHEMBL4096681)
Affinity DataIC50: 232nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246877(CHEMBL4069457)
Affinity DataIC50: 236nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246887(CHEMBL4082492)
Affinity DataIC50: 322nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246884(CHEMBL4075815)
Affinity DataIC50: 355nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246888(CHEMBL4064714)
Affinity DataIC50: 613nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246895(CHEMBL4066303)
Affinity DataIC50: 902nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246894(CHEMBL4087657)
Affinity DataIC50: 924nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246896(CHEMBL4081095)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246904(CHEMBL4075288)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246903(CHEMBL4101871)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246885(CHEMBL4100925)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246886(CHEMBL4088612)
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246883(CHEMBL4069230)
Affinity DataIC50: 3.43E+3nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246902(CHEMBL4076637)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)