BindingDB PrimarySearch

Found 40 Enz. Inhib. hit(s) with all data for entry = 50002051

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50162774(ABT-199 | US11420968, Example ABT-199 | Venetoclax)

IC50: 7.40nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50270877((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...)

IC50: 8.20nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50270877((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...)

IC50: 10nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452765(CHEMBL4216466)

IC50: 13nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452760(CHEMBL4216380)

IC50: 13nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452765(CHEMBL4216466)

IC50: 15nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452767(CHEMBL4207006)

IC50: 15nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452762(CHEMBL4211198)

IC50: 17nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452768(CHEMBL4206829)

IC50: 21nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

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Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452761(CHEMBL4215940)

IC50: 26nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

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Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452759(CHEMBL4211496)

IC50: 27nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

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Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452766(CHEMBL4218405)

IC50: 29nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

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Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452768(CHEMBL4206829)

IC50: 34nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452769(CHEMBL4202464)

IC50: 35nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452760(CHEMBL4216380)

IC50: 38nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452777(CHEMBL4209752)

IC50: 41nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452772(CHEMBL4209621)

IC50: 46nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452773(CHEMBL4206007)

IC50: 47nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452767(CHEMBL4207006)

IC50: 49nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50162774(ABT-199 | US11420968, Example ABT-199 | Venetoclax)

IC50: 53nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452777(CHEMBL4209752)

IC50: 55nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452759(CHEMBL4211496)

IC50: 58nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452775(CHEMBL4208633)

IC50: 59nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452774(CHEMBL4210809)

IC50: 65nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452778(CHEMBL4218253)

IC50: 67nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452775(CHEMBL4208633)

IC50: 68nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452762(CHEMBL4211198)

IC50: 105nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452766(CHEMBL4218405)

IC50: 108nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452772(CHEMBL4209621)

IC50: 116nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452773(CHEMBL4206007)

IC50: 162nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452763(CHEMBL4213316)

IC50: 168nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452761(CHEMBL4215940)

IC50: 193nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452774(CHEMBL4210809)

IC50: 218nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452769(CHEMBL4202464)

IC50: 342nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452776(CHEMBL4204650)

IC50: 495nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452763(CHEMBL4213316)

IC50: >1.00E+3nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Apoptosis regulator Bcl-2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452764(CHEMBL4204583)

IC50: >1.00E+3nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452776(CHEMBL4204650)

IC50: >1.00E+3nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452778(CHEMBL4218253)

IC50: >1.00E+3nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Bcl-2-like protein 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL

BDBM50452764(CHEMBL4204583)

IC50: >1.00E+3nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed