Found 10 Enz. Inhib. hit(s) with all data for entry = 50001180 TargetHigh mobility group protein B1(Homo sapiens (Human))
The Feinstein Institute For Medical Research
Curated by ChEMBL
The Feinstein Institute For Medical Research
Curated by ChEMBL
Affinity DataKd: 1.03E+5nMAssay Description:Binding affinity to recombinant HMGB1 A box region (1 to 89 residues) (unknown origin) expressed Escherichia coli after 5 mins by fluorescence-based ...More data for this Ligand-Target Pair
TargetHigh mobility group protein B1(Homo sapiens (Human))
The Feinstein Institute For Medical Research
Curated by ChEMBL
The Feinstein Institute For Medical Research
Curated by ChEMBL
Affinity DataKd: 8.70E+4nMAssay Description:Binding affinity to recombinant HMGB1 B box region (90 to 175 residues) (unknown origin) expressed Escherichia coli after 5 mins by fluorescence-base...More data for this Ligand-Target Pair
TargetHigh mobility group protein B1(Homo sapiens (Human))
The Feinstein Institute For Medical Research
Curated by ChEMBL
The Feinstein Institute For Medical Research
Curated by ChEMBL
Affinity DataKd: 500nMAssay Description:Binding affinity to N-terminal 6His-tagged HMGB1 AI region (1 to 87 residues) (unknown origin) expressed in Escherichia coli JM109 by SPR assayMore data for this Ligand-Target Pair
TargetHigh mobility group protein B1(Homo sapiens (Human))
The Feinstein Institute For Medical Research
Curated by ChEMBL
The Feinstein Institute For Medical Research
Curated by ChEMBL
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to recombinant HMGB1 box A (unknown origin)More data for this Ligand-Target Pair
TargetLymphocyte antigen 96(Homo sapiens (Human))
The Feinstein Institute For Medical Research
Curated by ChEMBL
The Feinstein Institute For Medical Research
Curated by ChEMBL
Affinity DataKd: 650nMAssay Description:Binding affinity to human MD-2 (17 to 160 residues) assessed as reduction in MD-2 binding to human HMGB1 after 7 mins by SPR assayMore data for this Ligand-Target Pair
TargetHigh mobility group protein B1(Homo sapiens (Human))
The Feinstein Institute For Medical Research
Curated by ChEMBL
The Feinstein Institute For Medical Research
Curated by ChEMBL
Affinity DataKd: 1.5nMAssay Description:Binding affinity to recombinant HMGB1 box B (unknown origin)More data for this Ligand-Target Pair
TargetToll-like receptor 4/MD-2(Homo sapiens (Human))
The Feinstein Institute For Medical Research
Curated by ChEMBL
The Feinstein Institute For Medical Research
Curated by ChEMBL
Affinity DataKd: 5.95E+3nMAssay Description:Binding affinity to recombinant human 10His-tagged TLR4 (24 to 631 residues)/recombinant human 10His-tagged MD2 (17 to 160 residues) after 5 mins by ...More data for this Ligand-Target Pair
TargetHigh mobility group protein B1(Homo sapiens (Human))
The Feinstein Institute For Medical Research
Curated by ChEMBL
The Feinstein Institute For Medical Research
Curated by ChEMBL
Affinity DataKd: 24nMAssay Description:Binding affinity to N-terminal 6His-tagged HMGB1 Bj region (88 to 181 residues) (unknown origin) expressed in Escherichia coli JM109 by SPR assayMore data for this Ligand-Target Pair
TargetHigh mobility group protein B1(Homo sapiens (Human))
The Feinstein Institute For Medical Research
Curated by ChEMBL
The Feinstein Institute For Medical Research
Curated by ChEMBL
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to recombinant HMGB1 box B (unknown origin)More data for this Ligand-Target Pair
TargetHigh mobility group protein B1(Homo sapiens (Human))
The Feinstein Institute For Medical Research
Curated by ChEMBL
The Feinstein Institute For Medical Research
Curated by ChEMBL
Affinity DataKd: 1.5nMAssay Description:Binding affinity to recombinant HMGB1 box A (unknown origin)More data for this Ligand-Target Pair
