Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50000368
LigandChemical structure of BindingDB Monomer ID 50247642BDBM50247642(CHEMBL4072240)
Affinity DataIC50: 3nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 261607BDBM261607(US9708272, 18 | US10513499, Compound 18 | US112546...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 261521BDBM261521(US9708272, 4 | US10513499, Compound 4 | US11254644...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Tes Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126147BDBM50126147(CHEMBL3629571)
Affinity DataIC50: 20nMAssay Description:Inhibition of rat liver KMO using [3,5-3H]-kynurenine substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 261511BDBM261511(US9708272, 1 | US10513499, Compound 1 | US11254644...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 261535BDBM261535(US9708272, 6 | US10513499, Compound 6 | US11254644...)
Affinity DataIC50: 89nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 261588BDBM261588(US9708272, 11 | US10513499, Compound 11 | US112546...)
Affinity DataIC50: 99nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Tes Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50247642BDBM50247642(CHEMBL4072240)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human CYP2C19 expressed in baculosomes expression system using fluorogenic-BOMCC as substrate by fluorescent homogeneous as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 261602BDBM261602(US9708272, 13 | US10513499, Compound 13 | US112546...)
Affinity DataIC50: 151nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 261610BDBM261610(US9708272, 22 | US10513499, Compound 22 | US112546...)
Affinity DataIC50: 316nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Tes Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061907BDBM50061907(meta-nitrobenzoyl)alanine | 2-Amino-4-(3-nitro-phe...)
Affinity DataIC50: 900nMAssay Description:Inhibition of rat liver KMO using [3,5-3H]-kynurenine substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 261603BDBM261603(US9708272, 14 | US10513499, Compound 14 | US112546...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50247648BDBM50247648(CHEMBL4082726)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 261555BDBM261555(US9708272, 10 | US10513499, Compound 10 | US112546...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50247652BDBM50247652(CHEMBL4093002)
Affinity DataIC50: 3.35E+3nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50247643BDBM50247643(CHEMBL1082811)
Affinity DataIC50: 4.45E+3nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Tes Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 261607BDBM261607(US9708272, 18 | US10513499, Compound 18 | US112546...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP2C19 expressed in baculosomes expression system using fluorogenic-BOMCC as substrate by fluorescent homogeneous as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A1(Rat)
Tes Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 261607BDBM261607(US9708272, 18 | US10513499, Compound 18 | US112546...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant rat CYP3A1 expressed in baculosomes expression system using fluorogenic-BOMCC as substrate by fluorescent homogeneous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Tes Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 261607BDBM261607(US9708272, 18 | US10513499, Compound 18 | US112546...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in baculosomes expression system using fluorogenic-BOMCC as substrate by fluorescent homogeneous ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Tes Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 261607BDBM261607(US9708272, 18 | US10513499, Compound 18 | US112546...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in baculosomes expression system using fluorogenic-BOMCC as substrate by fluorescent homogeneous ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126148BDBM50126148(CHEMBL3629572)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of rat liver KAT2 using [3H]-kynurenine incubated for 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed