Compile Data Set for Download or QSAR
maximum 50k data
Found 52 Enz. Inhib. hit(s) with all data for entry = 50001610
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287566(CHEMBL4160797 | US11572354, Compound 10m)
Affinity DataIC50:  34nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287562(CHEMBL4173383 | US11572354, Compound 10e)
Affinity DataIC50:  38nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287581(CHEMBL4173791 | US11572354, Compound 10d)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287567(CHEMBL4165309 | US11572354, Compound 10l)
Affinity DataIC50:  113nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287565(CHEMBL4163084 | US11572354, Compound 10c)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287577(CHEMBL4165466 | US11572354, Compound 10f)
Affinity DataIC50:  322nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287569(CHEMBL4177139 | US11572354, Compound 10b)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287579(CHEMBL4166936 | US11572354, Compound 9k)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287561(CHEMBL4163441 | US11572354, Compound 9f)
Affinity DataIC50:  3.81E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287560(CHEMBL4166521 | US11572354, Compound 10a)
Affinity DataIC50:  4.44E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287572(CHEMBL4164194 | US11572354, Compound 10g)
Affinity DataIC50:  4.64E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287582(CHEMBL4174828 | US11572354, Compound 9j)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287570(CHEMBL4165816 | US11572354, Compound 9a)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287573(CHEMBL4159712 | US11572354, Compound 9h)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287575(CHEMBL4175513 | US11572354, Compound 10j)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287571(CHEMBL4166900)
Affinity DataIC50:  2.16E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287576(CHEMBL4167644 | US11572354, Compound 10i)
Affinity DataIC50:  2.27E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287574(CHEMBL4162371 | US11572354, Compound 9c)
Affinity DataIC50:  3.42E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287583(CHEMBL4170293 | US11572354, Compound 9b)
Affinity DataIC50:  3.48E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287564(CHEMBL4175924 | US11572354, Compound 10k)
Affinity DataIC50:  4.48E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM24656(4-PIM | 4-Phenylimidazole | 4-phenyl-1H-imidazole ...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of human IDO1 expressed in Escherichia coli BL21 (DE3) using L-tryptophan as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287584(CHEMBL4170338 | US11572354, Compound 9i)
Affinity DataIC50:  5.06E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287566(CHEMBL4160797 | US11572354, Compound 10m)
Affinity DataIC50:  5.44E+4nMAssay Description:Inhibition of recombinant human 6His-tagged TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in kynurenine production using L-tryp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287568(CHEMBL4172071 | US11572354, Compound 10h)
Affinity DataIC50:  8.33E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287567(CHEMBL4165309 | US11572354, Compound 10l)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibition of recombinant human 6His-tagged TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in kynurenine production using L-tryp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287580(CHEMBL4177510 | US11572354, Compound 9e)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287563(CHEMBL4174143 | US11572354, Compound 9g)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287579(CHEMBL4166936 | US11572354, Compound 9k)
Affinity DataEC50:  9.97E+3nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287569(CHEMBL4177139 | US11572354, Compound 10b)
Affinity DataEC50:  1.87E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287584(CHEMBL4170338 | US11572354, Compound 9i)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287583(CHEMBL4170293 | US11572354, Compound 9b)
Affinity DataEC50:  1.08E+4nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287564(CHEMBL4175924 | US11572354, Compound 10k)
Affinity DataEC50:  6.40E+3nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287568(CHEMBL4172071 | US11572354, Compound 10h)
Affinity DataEC50:  4.56E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287565(CHEMBL4163084 | US11572354, Compound 10c)
Affinity DataEC50:  1.45E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287562(CHEMBL4173383 | US11572354, Compound 10e)
Affinity DataEC50:  890nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287561(CHEMBL4163441 | US11572354, Compound 9f)
Affinity DataEC50:  6.92E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287563(CHEMBL4174143 | US11572354, Compound 9g)
Affinity DataEC50:  1.07E+4nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287560(CHEMBL4166521 | US11572354, Compound 10a)
Affinity DataEC50:  9.12E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287573(CHEMBL4159712 | US11572354, Compound 9h)
Affinity DataEC50:  9.47E+3nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287570(CHEMBL4165816 | US11572354, Compound 9a)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataEC50:  8.70nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287580(CHEMBL4177510 | US11572354, Compound 9e)
Affinity DataEC50:  4.59E+3nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287582(CHEMBL4174828 | US11572354, Compound 9j)
Affinity DataEC50:  5.01E+3nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287567(CHEMBL4165309 | US11572354, Compound 10l)
Affinity DataEC50:  320nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287571(CHEMBL4166900)
Affinity DataEC50:  4.29E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287581(CHEMBL4173791 | US11572354, Compound 10d)
Affinity DataEC50:  1.04E+3nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287577(CHEMBL4165466 | US11572354, Compound 10f)
Affinity DataEC50:  480nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287572(CHEMBL4164194 | US11572354, Compound 10g)
Affinity DataEC50:  4.19E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287576(CHEMBL4167644 | US11572354, Compound 10i)
Affinity DataEC50:  6.26E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50287575(CHEMBL4175513 | US11572354, Compound 10j)
Affinity DataEC50:  5.55E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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