Compile Data Set for Download or QSAR
Report error Found 80 Enz. Inhib. hit(s) with all data for entry = 50000272
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244490BDBM50244490(CHEMBL4102992)
Affinity DataKi:  0.320nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 111951BDBM111951(US8618107, 197)
Affinity DataKi:  0.350nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244489BDBM50244489(CHEMBL4095379)
Affinity DataKi:  0.370nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244491BDBM50244491(CHEMBL4092794)
Affinity DataKi:  0.430nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244488BDBM50244488(CHEMBL4069790)
Affinity DataKi:  0.430nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244494BDBM50244494(CHEMBL4090117)
Affinity DataKi:  0.450nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244467BDBM50244467(CHEMBL4063638)
Affinity DataKi:  0.580nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244502BDBM50244502(CHEMBL4085043)
Affinity DataKi:  0.650nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 111952BDBM111952(US8618107, 210)
Affinity DataKi:  0.690nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244493BDBM50244493(CHEMBL4070991)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244440BDBM50244440(CHEMBL4065122)
Affinity DataKi:  0.910nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244492BDBM50244492(CHEMBL4087543)
Affinity DataKi:  0.960nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244500BDBM50244500(CHEMBL4093188)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244486BDBM50244486(CHEMBL4097832)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244501BDBM50244501(CHEMBL4062634)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244440BDBM50244440(CHEMBL4065122)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BTK in human isolated primary B cells assessed as inhibition of anti-IgM-induced cell proliferation by [3H]thymidine incorporation assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244497BDBM50244497(CHEMBL4074792)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244440BDBM50244440(CHEMBL4065122)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of BTK in human mononuclear cell-derived monocytes assessed as inhibition of FCgammaR3 activation-induced TNFalpha production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244440BDBM50244440(CHEMBL4065122)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of BTK in human isolated primary B cells assessed as inhibition of CD40L-induced cell proliferation by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244495BDBM50244495(CHEMBL4066176)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244464BDBM50244464(CHEMBL4085477)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244499BDBM50244499(CHEMBL4086408)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244483BDBM50244483(CHEMBL4082268)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244484BDBM50244484(CHEMBL4060356)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244469BDBM50244469(CHEMBL4090946)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244440BDBM50244440(CHEMBL4065122)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of anti-IgM-induced BTK phosphorylation at Y233 in human primary B cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244485BDBM50244485(CHEMBL4071754)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244487BDBM50244487(CHEMBL4079803)
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244468BDBM50244468(CHEMBL4104307)
Affinity DataKi:  4.20nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244502BDBM50244502(CHEMBL4085043)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244466BDBM50244466(CHEMBL4075845)
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244498BDBM50244498(CHEMBL4101904)
Affinity DataKi:  6.30nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244465BDBM50244465(CHEMBL4075253)
Affinity DataKi:  6.90nMAssay Description:Inhibition of human recombinant C-terminal polyhistidine tagged BTK (1 to 659 residues)-mediated synthetic peptide substrate phosphorylation expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244440BDBM50244440(CHEMBL4065122)
Affinity DataIC50: 8nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244497BDBM50244497(CHEMBL4074792)
Affinity DataIC50: 10nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244440BDBM50244440(CHEMBL4065122)
Affinity DataIC50: 11nMAssay Description:Inhibition of anti-IgM-induced BTK phosphorylation at Y233 in human whole blood after 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357312BDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 12nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244491BDBM50244491(CHEMBL4092794)
Affinity DataIC50: 13nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244499BDBM50244499(CHEMBL4086408)
Affinity DataIC50: 15nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244492BDBM50244492(CHEMBL4087543)
Affinity DataIC50: 16nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244496BDBM50244496(CHEMBL4095248)
Affinity DataIC50: 16nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244489BDBM50244489(CHEMBL4095379)
Affinity DataIC50: 17nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244488BDBM50244488(CHEMBL4069790)
Affinity DataIC50: 24nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244490BDBM50244490(CHEMBL4102992)
Affinity DataIC50: 28nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 111951BDBM111951(US8618107, 197)
Affinity DataIC50: 28nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244440BDBM50244440(CHEMBL4065122)
Affinity DataIC50: 31nMAssay Description:Inhibition of BTK in human whole blood derived-basophils assessed as suppression of IgE mediated-FcepsilonR ligation-stimulated CD63 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244494BDBM50244494(CHEMBL4090117)
Affinity DataIC50: 32nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244486BDBM50244486(CHEMBL4097832)
Affinity DataIC50: 32nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244485BDBM50244485(CHEMBL4071754)
Affinity DataIC50: 33nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244501BDBM50244501(CHEMBL4062634)
Affinity DataIC50: 37nMAssay Description:Inhibition of BTK in human whole blood-derived CD19+ B cells assessed as suppression of anti-IgM stimulated-CD69 expression preincubated for 1 hr fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details Article
PubMed
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