Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50000620
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255625(CHEMBL4070714)
Affinity DataIC50:  630nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells assessed as inhibition of LPS-induced NF-kappaB activation-mediated SEAP production pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255625(CHEMBL4070714)
Affinity DataIC50:  1.70E+3nMAssay Description:Antagonist activity at human TLR4 expressed in mouse RAW blue cells assessed as inhibition of LPS-induced NF-kappaB activation-mediated SEAP producti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255632(CHEMBL4100044)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells assessed as inhibition of LPS-induced NF-kappaB activation-mediated SEAP production pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255626(CHEMBL4069693)
Affinity DataIC50:  5.45E+3nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells assessed as inhibition of LPS-induced NF-kappaB activation-mediated SEAP production pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255632(CHEMBL4100044)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255626(CHEMBL4069693)
Affinity DataIC50:  4.20E+4nMAssay Description:Antagonist activity at human TLR4 expressed in mouse RAW blue cells assessed as inhibition of LPS-induced NF-kappaB activation-mediated SEAP producti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLymphocyte antigen 96(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255633(CHEMBL4091601)
Affinity DataKd:  6.70E+4nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLymphocyte antigen 96(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255625(CHEMBL4070714)
Affinity DataKd:  1.40E+4nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLymphocyte antigen 96(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255632(CHEMBL4100044)
Affinity DataKd:  3.00E+3nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLymphocyte antigen 96(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50255626(CHEMBL4069693)
Affinity DataKd:  2.20E+4nMAssay Description:Binding to C-terminal His6-tagged human MD2 expressed in Pichia pastoris GS115 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed