Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50002240
TargetTyrosine-protein kinase Blk(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human BLK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455745(CHEMBL4214532)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human TEC using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Blk(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human BLK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455742(CHEMBL4206284)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human ErbB4 using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455754(CHEMBL4202814)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human EGFR using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human EGFR using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human TEC using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human ErbB2 using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human ErbB4 using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455749(CHEMBL4209773)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455744(CHEMBL4217114)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human TXK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455747(CHEMBL4214872 | US10829491, Compound S2)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455739(CHEMBL4217006)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455748(CHEMBL4211579 | US10829491, Compound S1)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human TXK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455740(CHEMBL4208616)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455746(CHEMBL4215249 | US10829491, Compound S19)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455743(CHEMBL4203064)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455756(CHEMBL4217820)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455762(CHEMBL4203739)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455757(CHEMBL4203826)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant human RET using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455761(CHEMBL4209342 | US10829491, Compound S3)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of recombinant human BMX using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455737(CHEMBL4214492 | US10829491, Compound S18)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455758(CHEMBL4203756)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 10nMAssay Description:Inhibition of BTK autophosphorylation at Y223 in human TMD8 cells after 4 hrs by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human ITK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant full-length N-terminal His-tagged human BTK C481S mutant expressed in baculovirus infected Sf9 insect cells using Poly(Glu,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human ITK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human RET using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human ErbB2 using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455752(CHEMBL4204398)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455751(CHEMBL4215470)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455760(CHEMBL4216788)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455741(CHEMBL4207689)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human FLT3 using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455759(CHEMBL4217471)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 174nMAssay Description:Inhibition of recombinant human BMX using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455738(CHEMBL4211949)
Affinity DataIC50: 215nMAssay Description:Inhibition of recombinant human PDGFR-beta using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455753(CHEMBL4209048)
Affinity DataIC50: 417nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455739(CHEMBL4217006)
Affinity DataIC50: 464nMAssay Description:Inhibition of recombinant full-length N-terminal His-tagged human BTK C481S mutant expressed in baculovirus infected Sf9 insect cells using Poly(Glu,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50455750(CHEMBL4218760)
Affinity DataIC50: 725nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human CSF1R using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
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