Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 50001265
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50187693(CHEMBL3186509)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241106(US9409895, 17 | US9630945, 17)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241109(US9409895, 20 | US9630945, 20)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50274089(CHEMBL4128124)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241108(US9409895, 19 | US9630945, 19)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241133(US9409895, 44 | US9630945, 44)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50274085(CHEMBL4129507)
Affinity DataIC50:  8nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241106(US9409895, 17 | US9630945, 17)
Affinity DataIC50:  9nMAssay Description:Inhibition of ATX in human serum assessed as reduction in LPA 18:1 levels after 3 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50274084(CHEMBL4126051)
Affinity DataIC50:  10nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50274081(CHEMBL4127145)
Affinity DataIC50:  18nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241121(US9409895, 32 | US9630945, 32)
Affinity DataIC50:  25nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241143(US9409895, 53 | US9630945, 53)
Affinity DataIC50:  39nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241126(US9409895, 37 | US9630945, 37)
Affinity DataIC50:  55nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241110(US9409895, 21 | US9630945, 21)
Affinity DataIC50:  86nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241107(US9409895, 18 | US9630945, 18)
Affinity DataIC50:  93nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50274086(CHEMBL4130315)
Affinity DataIC50:  130nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241124(US9409895, 35 | US9630945, 35)
Affinity DataIC50:  150nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50274087(CHEMBL4129365)
Affinity DataIC50:  170nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241148(US9409895, 58 | US9630945, 58)
Affinity DataIC50:  206nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50274088(CHEMBL4127038)
Affinity DataIC50:  240nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241116(US9409895, 27 | US9630945, 27)
Affinity DataIC50:  370nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50274112(CHEMBL4127963)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50187693(CHEMBL3186509)
Affinity DataIC50:  2.70E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241121(US9409895, 32 | US9630945, 32)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells at -90 mV holding potential by Qpatch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241124(US9409895, 35 | US9630945, 35)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells at -90 mV holding potential by Qpatch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241108(US9409895, 19 | US9630945, 19)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells at -90 mV holding potential by Qpatch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241109(US9409895, 20 | US9630945, 20)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells at -90 mV holding potential by Qpatch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241106(US9409895, 17 | US9630945, 17)
Affinity DataIC50:  2.09E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells at -90 mV holding potential by Qpatch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM241121(US9409895, 32 | US9630945, 32)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed