Found 60 Enz. Inhib. hit(s) with all data for entry = 50002458 TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human His-tagged p85alpha/p110alpha E545K mutant expressed in insect cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human His-tagged p85alpha/p110alpha E542K mutant expressed in insect cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human His-tagged p85alpha/p110alpha E545K mutant expressed in insect cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of p110alpha H1047R mutant (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of p110alpha H1047R mutant (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human His-tagged p85alpha/p110alpha E542K mutant expressed in insect cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110delta/recombinant human full length p85alpha expressed in baculovirus infected...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 125nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110delta/recombinant human full length p85alpha expressed in baculovirus infected...More data for this Ligand-Target Pair
3D Structure (crystal)TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 164nMAssay Description:Inhibition of recombinant human full-length His-tagged p110gamma expressed in baculovirus expression system using PIP2 as substrate measured after 1 ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 186nMAssay Description:Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4EBP1 a...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 189nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 197nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110delta/recombinant human full length p85alpha expressed in baculovirus infected...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 204nMAssay Description:Inhibition of recombinant human full-length His-tagged p110gamma expressed in baculovirus expression system using PIP2 as substrate measured after 1 ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 223nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 234nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/recombinant human full length p85alpha expressed in baculovirus infected ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110delta/recombinant human full length p85alpha expressed in baculovirus infected...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 264nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/recombinant human full length p85alpha expressed in baculovirus infected ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 288nMAssay Description:Inhibition of recombinant human full-length His-tagged p110gamma expressed in baculovirus expression system using PIP2 as substrate measured after 1 ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 314nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/recombinant human full length p85alpha expressed in baculovirus infected ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 321nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 372nMAssay Description:Inhibition of recombinant human full-length His-tagged p110gamma expressed in baculovirus expression system using PIP2 as substrate measured after 1 ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 376nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/recombinant human full length p85alpha expressed in baculovirus infected ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4EBP1 a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4EBP1 a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Shanghai Haiyan Pharmaceutical Technology
Curated by ChEMBL
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4EBP1 a...More data for this Ligand-Target Pair
