TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 47nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 69nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 71nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 75nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 124nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 136nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 141nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 163nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 239nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataKi: 660nMAssay Description:Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of CYP3A4 in in human liver microsomes in presence of NADPH regeneration mixture using luciferin IPA-OH substrate by P450-Glo assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 in in human liver microsomes in presence of NADPH regeneration mixture using luciferin IPA-OH substrate by P450-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 in in human liver microsomes in presence of NADPH regeneration mixture using luciferin IPA-OH substrate by P450-Glo assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair