BindingDB PrimarySearch_ki

Found 98 Enz. Inhib. hit(s) with all data for entry = 50002859

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)

IC50: 1.60nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-substrate...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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3D Structure (crystal)

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)

IC50: 2.10nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)

IC50: 4.30nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
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Details Article PubMed PDB

3D Structure (crystal)

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463796(CHEMBL4244148)

IC50: 6.20nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463800(CHEMBL4249310)

IC50: 9.90nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463792(CHEMBL4245422)

IC50: 16nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463799(CHEMBL4241272)

IC50: 19nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463801(CHEMBL4249492)

IC50: 21nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463795(CHEMBL4248202)

IC50: 32nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)

IC50: 36nMAssay Description:Inhibition of recombinant human GST-tagged TYK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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PDB

3D Structure (crystal)

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463794(CHEMBL4249872)

IC50: 36nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463788(CHEMBL4238357)

IC50: 56nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463798(CHEMBL4238190)

IC50: 58nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463788(CHEMBL4238357)

IC50: 78nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463817(CHEMBL4244570)

IC50: 87nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463818(CHEMBL4238436)

IC50: 94nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463818(CHEMBL4238436)

IC50: 104nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463807(CHEMBL4248451)

IC50: 112nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-substrate...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463819(CHEMBL4240663)

IC50: 115nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463807(CHEMBL4248451)

IC50: 124nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463792(CHEMBL4245422)

IC50: 126nMAssay Description:Inhibition of BTK (unknown origin) using TK-substrate-biotin measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463810(CHEMBL4242842)

IC50: 143nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463814(CHEMBL4244856)

IC50: 144nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463807(CHEMBL4248451)

IC50: 147nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463788(CHEMBL4238357)

IC50: 147nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-substrate...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463802(CHEMBL4239312)

IC50: 154nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463801(CHEMBL4249492)

IC50: 159nMAssay Description:Inhibition of BTK (unknown origin) using TK-substrate-biotin measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463818(CHEMBL4238436)

IC50: 165nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-substrate...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463819(CHEMBL4240663)

IC50: 168nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463796(CHEMBL4244148)

IC50: 180nMAssay Description:Inhibition of BTK (unknown origin) using TK-substrate-biotin measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463789(CHEMBL4244213)

IC50: 189nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463797(CHEMBL4240238)

IC50: 197nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463814(CHEMBL4244856)

IC50: 197nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463800(CHEMBL4249310)

IC50: 203nMAssay Description:Inhibition of BTK (unknown origin) using TK-substrate-biotin measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463808(CHEMBL4241559)

IC50: 267nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463820(CHEMBL4249784)

IC50: 278nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463793(CHEMBL4245633)

IC50: 282nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463805(CHEMBL4237788)

IC50: 315nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463804(CHEMBL4248256)

IC50: 324nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463795(CHEMBL4248202)

IC50: 342nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-substrate...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463790(CHEMBL4245728)

IC50: 367nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463790(CHEMBL4245728)

IC50: 374nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463793(CHEMBL4245633)

IC50: 395nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463796(CHEMBL4244148)

IC50: 396nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463794(CHEMBL4249872)

IC50: 420nMAssay Description:Inhibition of BTK (unknown origin) using TK-substrate-biotin measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463797(CHEMBL4240238)

IC50: 469nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463799(CHEMBL4241272)

IC50: 481nMAssay Description:Inhibition of BTK (unknown origin) using TK-substrate-biotin measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463804(CHEMBL4248256)

IC50: 497nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain expressed in baculovirus expression system using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463817(CHEMBL4244570)

IC50: 497nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-substrate...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50463798(CHEMBL4238190)

IC50: 497nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-substrate...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

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