Found 7 Enz. Inhib. hit(s) with all data for entry = 50003121 TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Inhibition of FAM-tagged p53-based fluorescent probe binding to human His-tagged MDM2 (1 to 118 residues) after 15 mins by fluorescence polarization ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of p53 protein binding to recombinant human GST-tagged MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant p53 protein binding to recombinant human MDM2 by surface plasmon resonance methodMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant p53 protein binding to recombinant human MDM2 by surface plasmon resonance methodMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant p53 protein binding to recombinant human MDM2 by surface plasmon resonance methodMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Affinity DataKd: 3.10E+3nMAssay Description:Binding affinity to recombinant human MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) assessed as reduction in tryptophan fluoresce...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Affinity DataKd: 500nMAssay Description:Binding affinity to recombinant human MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) assessed as reduction in tryptophan fluoresce...More data for this Ligand-Target Pair
