Found 8 Enz. Inhib. hit(s) with all data for entry = 50011526 
Affinity DataKi: <0.0250nMAssay Description:Inhibition of ROS1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of ROS1 (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 0.700nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase ROS/Sodium-dependent phosphate transport protein 2B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Inhibition of SLC34A2-ROS1 (unknown origin) expressed in human HCC78 cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain/Proto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Inhibition of CD74-ROS1 (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain/Proto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of CD74-ROS1 (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase ROS/Sodium-dependent phosphate transport protein 2B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of SLC34A2-ROS1 (unknown origin) expressed in human HCC78 cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair
