Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50007139
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50:  23nMAssay Description:Inhibition of CDK5/p35 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50:  24nMAssay Description:Inhibition of CDK2/CyclinE (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50309910(CHEMBL608154 | ML-120B | N-(6-chloro-7-methoxy-9H-...)
Affinity DataIC50:  465nMAssay Description:Inhibition of IKKbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50:  911nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LRRK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IKKbeta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin) after 22 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAPK14 (unknown origin) after 22 mins by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Eppley Institute For Research In Cancer And Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50506700(CHEMBL4439395)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed