Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 50007154
TargetChymase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50139758((2-Naphthalen-2-yl-1-naphthalen-1-yl-2-oxo-ethyl)-...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of chymase in human mast cells using Suc-Ala-Ala-Pro-Phe-(p-nitroanilide) as substrate for 15 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50506770(CHEMBL4472052)
Affinity DataKi:  38nMAssay Description:Inhibition of cathepsin G in human neutrophils using Suc-Ala-Ala-Pro-Phe-(p-nitroanilide) as substrate for 15 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50058204((S)-2-{[6-((R)-2-Amino-3-mercapto-propylamino)-nap...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of FTase (unknown origin) assessed as reduction in transfer of [3H]FPP to Ha-RasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50058199((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-nap...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of FTase (unknown origin) assessed as reduction in transfer of [3H]FPP to Ha-RasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50058208((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-nap...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of FTase (unknown origin) assessed as reduction in transfer of [3H]FPP to Ha-RasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50058204((S)-2-{[6-((R)-2-Amino-3-mercapto-propylamino)-nap...)
Affinity DataIC50:  17nMAssay Description:Inhibition of FTase (unknown origin) assessed as reduction in transfer of [3H]FPP to Ki-RasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50058193((S)-2-{[6-((R)-2-Amino-3-mercapto-propylamino)-nap...)
Affinity DataIC50:  80nMAssay Description:Inhibition of FTase (unknown origin) assessed as reduction in transfer of [3H]FPP to Ha-RasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50506773(CHEMBL4460768)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at angiotensin-2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50058193((S)-2-{[6-((R)-2-Amino-3-mercapto-propylamino)-nap...)
Affinity DataIC50:  500nMAssay Description:Inhibition of FTase (unknown origin) assessed as reduction in transfer of [3H]FPP to Ki-RasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50506771(CHEMBL4537621)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50506772(CHEMBL4471015)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed