Found 13 Enz. Inhib. hit(s) with all data for entry = 50007162 TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 3.49E+3nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 4.46E+3nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
3D Structure (crystal)TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 5.24E+3nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 6.15E+3nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 1.27E+4nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 1.72E+4nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 2.12E+4nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory Of Molecular Pharmacology And Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 4.98E+4nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
