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Found 5 Enz. Inhib. hit(s) with all data for entry = 50003205
TargetProthrombin(Homo sapiens (Human))
Institute Of Medicinal And Aromatic Plants

Curated by ChEMBL
LigandPNGBDBM50218197((-)-beta-Sitosterol | (24R)-Ethylcholest-5-en-3bet...)
Affinity DataKi:  267nMAssay Description:Uncompetitive inhibition of human thrombin using T1637 as substrate by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Institute Of Medicinal And Aromatic Plants

Curated by ChEMBL
LigandPNGBDBM50218197((-)-beta-Sitosterol | (24R)-Ethylcholest-5-en-3bet...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of thrombin in human washed platelets assessed as reduction in thrombin-induced platelet aggregation after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Institute Of Medicinal And Aromatic Plants

Curated by ChEMBL
LigandPNGBDBM50218197((-)-beta-Sitosterol | (24R)-Ethylcholest-5-en-3bet...)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of thrombin in human platelet rich plasma assessed as reduction in thrombin-induced platelet aggregation after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Institute Of Medicinal And Aromatic Plants

Curated by ChEMBL
LigandPNGBDBM50218197((-)-beta-Sitosterol | (24R)-Ethylcholest-5-en-3bet...)
Affinity DataIC50:  1.50E+6nMAssay Description:Inhibition of thrombin in human platelet rich plasma assessed as reduction in ADP-induced platelet aggregation after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Institute Of Medicinal And Aromatic Plants

Curated by ChEMBL
LigandPNGBDBM50218197((-)-beta-Sitosterol | (24R)-Ethylcholest-5-en-3bet...)
Affinity DataIC50:  1.50E+6nMAssay Description:Inhibition of thrombin in human platelet rich plasma assessed as reduction in arachidonic acid-induced platelet aggregation after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed