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Found 20 Enz. Inhib. hit(s) with all data for entry = 50006831
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503708(CHEMBL4457385)
Affinity DataKd:  1.07E+4nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK4 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503711(CHEMBL4447072)
Affinity DataKd:  8.90E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK3 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503710(CHEMBL4475584)
Affinity DataEC50:  500nMAssay Description:Inhibition of PDK1 (unknown origin) using PDH E1 as substrate measured after 30 mins by kinase-glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503711(CHEMBL4447072)
Affinity DataEC50:  4.64E+3nMAssay Description:Inhibition of PDK1 (unknown origin) using PDH E1 as substrate measured after 30 mins by kinase-glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50177027(CPC-211 | Ceresine | DCA | Sodium dichloroacetate)
Affinity DataEC50:  5.70E+6nMAssay Description:Inhibition of PDK1 (unknown origin) using PDH E1 as substrate measured after 30 mins by kinase-glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503710(CHEMBL4475584)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK1 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503711(CHEMBL4447072)
Affinity DataKd:  1.05E+4nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK1 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503710(CHEMBL4475584)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK2 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503708(CHEMBL4457385)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK2 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503709(CHEMBL4588123)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK2 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503710(CHEMBL4475584)
Affinity DataKd:  4.70E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK3 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503710(CHEMBL4475584)
Affinity DataKd:  2.60E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK4 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503709(CHEMBL4588123)
Affinity DataKd:  7.90E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK4 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503709(CHEMBL4588123)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK3 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503708(CHEMBL4457385)
Affinity DataEC50:  1.99E+3nMAssay Description:Inhibition of PDK1 (unknown origin) using PDH E1 as substrate measured after 30 mins by kinase-glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503708(CHEMBL4457385)
Affinity DataKd:  5.80E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK1 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503711(CHEMBL4447072)
Affinity DataKd:  1.59E+4nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK2 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503708(CHEMBL4457385)
Affinity DataKd:  7.80E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK3 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503709(CHEMBL4588123)
Affinity DataEC50:  420nMAssay Description:Inhibition of PDK1 (unknown origin) using PDH E1 as substrate measured after 30 mins by kinase-glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503709(CHEMBL4588123)
Affinity DataKd:  890nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK1 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed